Lab-in-a-tube: ultracompact components for on-chip capture and detection of individual micro-/nanoorganisms.

Numerical Study on Low Reynolds Mixing ofT-Shaped Micro-Mixers with Obstacles

Micromixers are one of the most crucial components of Lab-On-a-Chip devices with the intention of mixing and dispersion of reagents like small molecules and particles. The challenge facing micromixers is typically insufficient mixing efficiency in basic designs, which results in longer microchannels. Therefore, it is desirable to increase mixing efficiency, in order to decrease mixing length, w...

Design and Simulation of a Fluidic Micro-Bio-Sensor Based on Resonator Array

In this paper, a fluidic biosensor with possibility to fabricate by Micro-Electro-Mechanical Systems (MEMS) technology is proposed for biomedical mass detection and lab-on-chip applications. This is designed by electromechanical coupling of harmonic micromechanical resonators with harmonic springers as a mechanical resonator array. It can disperse mechanical wave along the array by electrostati...

PCR-based detection in a micro-fabricated platform.

We present a novel, on-chip system for the electrokinetic capture of bacterial cells and their identification using the polymerase chain reaction (PCR). The system comprises a glass-silicon platform with a set of micro-channels, -chambers, and -electrodes. A platinum thin film resistor, placed in the proximity of the chambers, is used for temperature monitoring. The whole chip assembly is mount...

Functional integration of DNA purification and concentration into a real time micro-PCR chip.

Microfluidic devices for on-chip amplification of DNA from various biological and environmental samples have gained extensive attention over the past decades with many applications including molecular diagnostics of disease, food safety and biological warfare testing. But the integration of sample preparation functions into the chip remains a major hurdle for practical application of the chip-b...

Comparison between Micro and Tube Virus Neutralization Tests for Detection of Serological Responses to Infectious Bursal Disease Virus Following Vaccination